After enduring nine months in microgravity, astronauts Butch Wilmore and Suni Williams are set to return to Earth, confronting significant physical and mental challenges. In this interview, biomedical engineer Dr. John Jaquish delves into the effects of prolonged space travel on bone density, muscle atrophy, cardiovascular health, and mental resilience. Discover the rigorous rehabilitation processes essential for their recovery and the implications for future long-duration space missions.